using(var client = new HttpClient())
{
   // do something with http client
}

 Unable to connect to the remote server
System.Net.Sockets.SocketException: Only one usage of each socket address (protocol/network address/port) is normally permitted.

using (var client = new HttpClient())
{
       var result = await client.GetAsync("http://example.com/");
}

for (int i = 0; i < 10; i++)
{
      using (var client = new HttpClient())
      {
            var result = await client.GetAsync("http://example.com/");
            Console.WriteLine(result.StatusCode);
      }
}

  TCP    192.168.1.6:13996      93.184.216.34:http     TIME_WAIT
  TCP    192.168.1.6:13997      93.184.216.34:http     TIME_WAIT
  TCP    192.168.1.6:13998      93.184.216.34:http     TIME_WAIT
  TCP    192.168.1.6:13999      93.184.216.34:http     TIME_WAIT
  TCP    192.168.1.6:14000      93.184.216.34:http     TIME_WAIT
  TCP    192.168.1.6:14001      93.184.216.34:http     TIME_WAIT
  TCP    192.168.1.6:14002      93.184.216.34:http     TIME_WAIT
  TCP    192.168.1.6:14003      93.184.216.34:http     TIME_WAIT
  TCP    192.168.1.6:14004      93.184.216.34:http     TIME_WAIT
  TCP    192.168.1.6:14005      93.184.216.34:http     TIME_WAIT

 [HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\Tcpip\Parameters\TcpTimedWaitDelay]

CancelPendingRequests
DeleteAsync
GetAsync
GetByteArrayAsync
GetStreamAsync
GetStringAsync
PostAsync
PutAsync
SendAsync

BaseAddress
DefaultRequestHeaders
MaxResponseContentBufferSize
Timeout

var sp = ServicePointManager.FindServicePoint(new Uri("http://thisisasample.com"));
sp.ConnectionLeaseTimeout = 60*1000; //In milliseconds

using System;
using System.Collections.Generic;
using System.Net.Http;

namespace HttpClientTips
{
    public interface IHttpClientFactory : IDisposable
    {
        HttpClient GetOrCreate(
            Uri baseAddress,
            IDictionary<string, string> defaultRequestHeaders = null,
            TimeSpan? timeout = null,
            long? maxResponseContentBufferSize = null,
            HttpMessageHandler handler = null);
    }
}

using System;
using System.Collections.Concurrent;
using System.Collections.Generic;
using System.Net;
using System.Net.Http;
using System.Threading;

namespace HttpClientTips
{
    /// <summary>
    /// Lifetime of this class should be set to `Singleton`.
    /// </summary>
    public class HttpClientFactory : IHttpClientFactory
    {
        // 'GetOrAdd' call on the dictionary is not thread safe and we might end up creating the HttpClient more than
        // once. To prevent this Lazy<> is used. In the worst case multiple Lazy<> objects are created for multiple
        // threads but only one of the objects succeeds in creating the HttpClient.
        private readonly ConcurrentDictionary<Uri, Lazy<HttpClient>> _httpClients =
                         new ConcurrentDictionary<Uri, Lazy<HttpClient>>();
        private const int ConnectionLeaseTimeout = 60 * 1000; // 1 minute

        public HttpClientFactory()
        {
            // Default is 2 minutes: https://msdn.microsoft.com/en-us/library/system.net.servicepointmanager.dnsrefreshtimeout(v=vs.110).aspx
            ServicePointManager.DnsRefreshTimeout = (int)TimeSpan.FromMinutes(1).TotalMilliseconds;
            // Increases the concurrent outbound connections
            ServicePointManager.DefaultConnectionLimit = 1024;
        }

        public HttpClient GetOrCreate(
           Uri baseAddress,
           IDictionary<string, string> defaultRequestHeaders = null,
           TimeSpan? timeout = null,
           long? maxResponseContentBufferSize = null,
           HttpMessageHandler handler = null)
        {
            return _httpClients.GetOrAdd(baseAddress,
                             uri => new Lazy<HttpClient>(() =>
                             {
                                 // Reusing a single HttpClient instance across a multi-threaded application means
                                 // you can't change the values of the stateful properties (which are not thread safe),
                                 // like BaseAddress, DefaultRequestHeaders, MaxResponseContentBufferSize and Timeout.
                                 // So you can only use them if they are constant across your application and need their own instance if being varied.
                                 var client = handler == null ? new HttpClient { BaseAddress = baseAddress } :
                                               new HttpClient(handler, disposeHandler: false) { BaseAddress = baseAddress };
                                 setRequestTimeout(timeout, client);
                                 setMaxResponseBufferSize(maxResponseContentBufferSize, client);
                                 setDefaultHeaders(defaultRequestHeaders, client);
                                 setConnectionLeaseTimeout(baseAddress, client);
                                 return client;
                             },
                             LazyThreadSafetyMode.ExecutionAndPublication)).Value;
        }

        public void Dispose()
        {
            foreach (var httpClient in _httpClients.Values)
            {
                httpClient.Value.Dispose();
            }
        }

        private static void setConnectionLeaseTimeout(Uri baseAddress, HttpClient client)
        {
            // This ensures connections are used efficiently but not indefinitely.
            client.DefaultRequestHeaders.ConnectionClose = false; // keeps the connection open -> more efficient use of the client
            ServicePointManager.FindServicePoint(baseAddress).ConnectionLeaseTimeout = ConnectionLeaseTimeout; // ensures connections are not used indefinitely.
        }

        private static void setDefaultHeaders(IDictionary<string, string> defaultRequestHeaders, HttpClient client)
        {
            if (defaultRequestHeaders == null)
            {
                return;
            }
            foreach (var item in defaultRequestHeaders)
            {
                client.DefaultRequestHeaders.Add(item.Key, item.Value);
            }
        }

        private static void setMaxResponseBufferSize(long? maxResponseContentBufferSize, HttpClient client)
        {
            if (maxResponseContentBufferSize.HasValue)
            {
                client.MaxResponseContentBufferSize = maxResponseContentBufferSize.Value;
            }
        }

        private static void setRequestTimeout(TimeSpan? timeout, HttpClient client)
        {
            if (timeout.HasValue)
            {
                client.Timeout = timeout.Value;
            }
        }
    }
}

namespace HttpClientTips.Web
{
    public class Startup
    {
        public void ConfigureServices(IServiceCollection services)
        {
            services.AddSingleton<IHttpClientFactory, HttpClientFactory>();
            services.AddMvc();
        }

namespace HttpClientTips.Web.Controllers
{
    public class HomeController : Controller
    {
        private readonly IHttpClientFactory _httpClientFactory;
        public HomeController(IHttpClientFactory httpClientFactory)
        {
            _httpClientFactory = httpClientFactory;
        }

        public async Task<IActionResult> Index()
        {
            var host = new Uri("http://localhost:5000");
            var httpClient = _httpClientFactory.GetOrCreate(host);
            var responseMessage = await httpClient.GetAsync("home/about").ConfigureAwait(false);
            var responseContent = await responseMessage.Content.ReadAsStringAsync().ConfigureAwait(false);
            return Content(responseContent);
        }